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Aminophylline

 

 
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Aminophylline
 
 
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Aminophylline is a bronchodilator
Bronchodilator

A bronchodilator is a substance that Wiktionary:dilate#Verb the Bronchus and bronchioles, decreasing airway resistance and thereby facilitating airflow....
 drug combination
Drug combination

Terms ending in "flip" refer to drug combinations involving MDMA . Substitute the word "trip" and the drug combination involves LSD.Candy flipping or Candy Trip: MDMA and LSD...
 that contains theophylline
Theophylline

Theophylline, also known as dimethylxanthine, is a methylxanthine drug used in therapy for respiratory diseases such as COPD or asthma under a variety of brand names....
 and ethylenediamine in 2:1 ratio.

s more soluble in water than theophylline. White or slightly yellowish granules or powder, having a slight ammoniacal odor and a bitter taste. Upon exposure to air, it gradually loses ethylenediamine and absorbs carbon dioxide
Carbon dioxide

Carbon dioxide is a chemical compound composed of two oxygen atoms covalent bond to a single carbon atom. It is a gas at standard temperature and pressure and exists in Earth's atmosphere in this state....
 with the liberation of free theophylline. Its solutions are alkaline.






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Encyclopedia


Aminophylline is a bronchodilator
Bronchodilator

A bronchodilator is a substance that Wiktionary:dilate#Verb the Bronchus and bronchioles, decreasing airway resistance and thereby facilitating airflow....
 drug combination
Drug combination

Terms ending in "flip" refer to drug combinations involving MDMA . Substitute the word "trip" and the drug combination involves LSD.Candy flipping or Candy Trip: MDMA and LSD...
 that contains theophylline
Theophylline

Theophylline, also known as dimethylxanthine, is a methylxanthine drug used in therapy for respiratory diseases such as COPD or asthma under a variety of brand names....
 and ethylenediamine in 2:1 ratio.

Properties

It is more soluble in water than theophylline. White or slightly yellowish granules or powder, having a slight ammoniacal odor and a bitter taste. Upon exposure to air, it gradually loses ethylenediamine and absorbs carbon dioxide
Carbon dioxide

Carbon dioxide is a chemical compound composed of two oxygen atoms covalent bond to a single carbon atom. It is a gas at standard temperature and pressure and exists in Earth's atmosphere in this state....
 with the liberation of free theophylline. Its solutions are alkaline. One g dissolves in 25 mL of water to give a clear solution; 1 g dissolved in 5 mL of water crystallizes upon standing, but redissolves when a small amount of ethylenediamine is added. Insoluble in alcohol and in ether.

Mechanism of action

Aminophylline is less potent and shorter-acting than theophylline
Theophylline

Theophylline, also known as dimethylxanthine, is a methylxanthine drug used in therapy for respiratory diseases such as COPD or asthma under a variety of brand names....
. Its most common use is in the treatment of bronchial asthma.

Causes bronchodilatation, diuresis, CNS and cardiac stimulation, and gastric acid secretion by blocking phosphodiesterase which increases tissue concentrations of cyclic adenine monophosphate (cAMP) which in turn promotes catecholamine stimulation of lipolysis, glycogenolysis, and gluconeogenesis and induces release of epinephrine from adrenal medulla cells

Other uses


Aminophylline has shown some promise as a bodyfat reducer when used as a topical cream.

Brand names

  • Phyllocontin
  • Truphylline
  • Minomal R 175mg tab
  • Minomal R 350mg tab
  • Minomal SR 600mg tab