Acetyltransferase
Encyclopedia
Acetyltransferase is a type of transferase
Transferase
In biochemistry, a transferase is an enzyme that catalyzes the transfer of a functional group from one molecule to another . For example, an enzyme that catalyzed this reaction would be a transferase:In this example, A would be the donor, and B would be the acceptor...

 enzyme
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...

 that transfers an acetyl
Acetyl
In organic chemistry, acetyl is a functional group, the acyl with chemical formula COCH3. It is sometimes represented by the symbol Ac . The acetyl group contains a methyl group single-bonded to a carbonyl...

 group.

Examples include:
  • Histone acetyltransferase
    Histone acetyltransferase
    Histone acetyltransferases are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl CoA to form ε-N-acetyl lysine....

    s including CBP histone acetyltransferase
  • Choline acetyltransferase
    Choline acetyltransferase
    Choline acetyltransferase is an enzyme that is synthesized within the body of a neuron. It is then transferred to the nerve terminal via axoplasmic flow. The role of choline acetyltransferase is to join Acetyl-CoA to choline, resulting in the formation of the neurotransmitter acetylcholine...

  • Chloramphenicol acetyltransferase
    Chloramphenicol acetyltransferase
    Chloramphenicol acetyltransferase is a bacterial enzyme that detoxifies the antibiotic chloramphenicol and is responsible for chloramphenicol resistance in bacteria. This enzyme covalently attaches an acetyl group from acetyl-CoA to chloramphenicol, which prevents chloramphenicol from binding to...

  • Serotonin N-acetyl transferase
    Serotonin N-acetyl transferase
    Serotonin N-acetyl transferase also known as arylalkylamine N-acetyltransferase or AANAT is a protein that, in humans, is encoded by the AANAT gene.-Function:...

  • NatA Acetyltransferase
    NatA Acetyltransferase
    NatA Acetyltransferase, is an enzyme that serves to catalyze the addition of acetyl groups to various proteins emerging from the ribosome. Upon translation, the NatA binds to the ribosome and then "stretches" to the front end of the forming, or nascent, polypeptide, where it adds this acetyl group...

  • NatB acteyltransferase
    NatB acteyltransferase
    NatB acetyltransferase is an enzyme in the Saccharomyces cerevisiae that functions to catalyze the dehydration synthesis of the addition of an acetyl group onto a nascent polypeptide. A list of 18 proteins are known to be acetylated by this enzyme. The subclasses of proteins with abundances of the...

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