5'-phosphoribosyl-5-aminoimidazole
Encyclopedia
5'-Phosphoribosyl-5-aminoimidazole (or aminoimidazole ribotide) is an intermediate in the formation of purine
s. Thus, it is an intermediate in the adenine pathway
, and is synthesized from 5'-phosphoribosylformylglycinamidine
by AIR synthetase.
Purine
A purine is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Purines, including substituted purines and their tautomers, are the most widely distributed kind of nitrogen-containing heterocycle in nature....
s. Thus, it is an intermediate in the adenine pathway
Adenine pathway
The Adenine Pathway in yeast is a seven step pathway converting P-ribosyl-PP to adenine. This product is then either integrated into DNA, RNA, or a ribose diphosphate molecule ADP, the precursor of ATP, an essential intermediate storage molecule for most cellular processes.-Mechanism:The ADE series...
, and is synthesized from 5'-phosphoribosylformylglycinamidine
5'-Phosphoribosylformylglycinamidine
5'-Phosphoribosylformylglycinamidine is an intermediate in the synthesis of purines....
by AIR synthetase.
See also
- Phosphoribosylaminoimidazole carboxylasePhosphoribosylaminoimidazole carboxylasePhosphoribosylaminoimidazole carboxylase is an enzyme involved in nucleotide biosynthesis and in particular in purine biosynthesis...
- 5-(carboxyamino)imidazole ribonucleotide synthase5-(carboxyamino)imidazole ribonucleotide synthaseIn enzymology, a 5-imidazole ribonucleotide synthase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are ATP, 5-amino-1-imidazole , and HCO3−, whereas its 3 products are ADP, phosphate, and 5-carboxyamino-1-imidazole.This enzyme belongs to the family of...
- 5-(carboxyamino)imidazole ribonucleotide mutase5-(carboxyamino)imidazole ribonucleotide mutaseIn enzymology, a 5-imidazole ribonucleotide mutase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 5-carboxyamino-1-imidazole, and one product, 5-amino-1-imidazole-4-carboxylate.This enzyme belongs to the family of isomerases, specifically those...