4,4'-Thiodianiline
Encyclopedia
4,4'-Thiodianiline is an aromatic amine
Aromatic amine
An aromatic amine is an amine with an aromatic substituent - that is -NH2, -NH- or nitrogen group attached to an aromatic hydrocarbon, whose structure usually contains one or more benzene rings. Aniline is the simplest example....

 which is presumed to be carcinogen
Carcinogen
A carcinogen is any substance, radionuclide, or radiation that is an agent directly involved in causing cancer. This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes...

ic to humans.

Chemical structure and properties

TDA is not combustible, but when heated it may decompose to form irritating and toxic fumes. An analogue of TDA is dapsone
Dapsone
Dapsone is a medication most commonly used in combination with rifampicin and clofazimine as multidrug therapy for the treatment of Mycobacterium leprae infections . It is also second-line treatment for prophylaxis against Pneumocystis pneumonia caused by Pneumocystis jiroveci Dapsone...

.

Uses

TDA was used almost exclusively as a chemical intermediate in the production of three dyes: CI mordant yellow 16, millimg red G and milling red FR.

Toxicity

TDA has caused mutations in some strains of Salmonella typhimurium and has caused tumors in laboratory mice and rats.
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