1571 The Royal Exchange opens in London.
1611 William Shakespeare's romantic comedy ''The Tempest'' is presented for the first time, at Whitehall Palace in London.
1613 The Globe Theatre in London, England burns to the ground.
1675 The foundation stone of the Royal Greenwich Observatory in London is laid.
1715 "Edmund Halley's" total solar eclipse (the last one visible in London, United Kingdom for almost 900 years).
1766 In London, James Christie holds his first sale.
1768 In London, Philip Astley stages the first modern circus.
1772 The first traveler's cheques, which can be used in 90 European cities, go on sale in London.
1788 First edition of ''The Times'' of London, previously ''The Daily Universal Register'', is published.
1803 The Surrey Iron Railway, arguably the world's first public railway, opens in south London.
1809 The Royal Opera House in London opens.
1812 Work on London's Regent's Canal starts.
1814 London Beer Flood occurs in London, killing nine.
1814 ''The Times'' in London is for the first time printed by automatic, steam powered presses built by the German inventors Friedrich Koenig and Andreas Friedrich Bauer, signaling the beginning of the availability of newspapers to a mass audience.
1820 London's Regent's Canal opens.
1828 The St Katharine Docks opened in London.
1834 Much of the ancient structure of the Palace of Westminster in London is burnt to the ground.
1843 The ''News of the World'' tabloid begins publication in London.
1844 The Young Men's Christian Association (YMCA) is founded in London.
1848 Waterloo railway station in London opens.
1849 The Great Hall of Euston station in London is opened.
1851 Queen Victoria opens the Great Exhibition in London.
1852 Great Ormond St Hospital for Sick Children, London, admits its first patient.
1859 Westminster's Big Ben rang for the first time in London.
1866 The Royal Aeronautical Society is formed in London.
1873 Alexandra Palace in London burns down after being open for only 16 days.
1887 Bloody Sunday clashes in central London.
1888 The first of eleven unsolved brutal murders of women committed in or near the impoverished Whitechapel district in the East End of London, occurs.
1888 A recording of English composer Arthur Sullivan's The Lost Chord, one of the first recordings of music ever made, is played during a press conference introducing Thomas Edison's phonograph in London.
1889 The free Woolwich Ferry officially opens in east London.
1895 The first individual time trial for racing cyclists is held on a 50-mile course north of London.
1897 London becomes the world's first city to host licenced taxicabs.
1906 Vauxhall Bridge is opened in London.
1909 The Science Museum in London comes into existence as an independent entity.
1917 Silvertown explosion: 73 are killed and 400 injured in an explosion in a munitions plant in London.
1919 Lincoln's Inn in London admits its first female bar student.
1933 In London, 500,000 march against anti-Semitism.
1936 The International Surrealist Exhibition opens in London, England.
1936 The Jarrow March sets off for London.
1943 World War II: The discovery of a mass grave of Polish prisoners of war executed by Soviet forces in the Katyń Forest Massacre is announced, alienating the Western Allies, the Polish government in exile in London, from the Soviet Union.
1944 World War II: London is hit by a V2 rocket for the first time.
1945 Lord Haw Haw (William Joyce) is sentenced to death in London.
1951 The first regularly scheduled transatlantic flights begin between Idlewild Airport (now John F Kennedy International Airport) in New York City and Heathrow Airport in London, operated by El Al Israel Airlines.
1958 The CND Peace Symbol displayed in public for the first time in London.
1965 Train robber Ronald Biggs escapes from Wandsworth Prison, London.
1978 While walking across Waterloo Bridge in London, Bulgarian dissident Georgi Markov is assassinated by Bulgarian secret police agent Francesco Giullino by means of a ricin pellet fired from a specially-designed umbrella.
1981 A worldwide television audience of over 700 million people watch the wedding of Charles, Prince of Wales, and Lady Diana Spencer at St Paul's Cathedral in London.
1982 Hyde Park and Regents Park bombings: The Provisional IRA detonates two bombs in Hyde Park and Regents Park in central London, killing eight soldiers, wounding forty-seven people, and leading to the deaths of seven horses.
1984 Police Constable Yvonne Fletcher is killed by gunfire from the Libyan People's Bureau in London during a small demonstration outside the embassy. Ten others are wounded. The events lead to an 11-day siege of the building.
1997 In London scientists report the findings of the DNA analysis of a Neanderthal skeleton which support the "out of Africa theory" of human evolution placing an "African Eve" at 100,000 to 200,000 years ago.
1999 The Scottish Parliament is officially opened by Queen Elizabeth on the day that legislative powers are officially transferred from the old Scottish Office in London to the new devolved Scottish Executive in Edinburgh.
1999 The Ladbroke Grove rail crash in west London kills 31 people.