1515 King Francis I of France succeeds to the French throne.
1516 The Treaty of Noyon between France and Spain is signed. Francis I of France recognises Charles's claim to Naples, and Charles V, Holy Roman Emperor recognises Francis's claim to Milan.
1532 Henry VIII and François I sign a secret treaty against Emperor Charles V.
1534 French explorer Jacques Cartier plants a cross on the Gaspé Peninsula and takes possession of the territory in the name of Francis I of France.
1539 Treaty of Toledo signed by King Francis I of France and Holy Roman Emperor Charles V.